Testis-specific proteins and their role in contraceptive vaccine development.
نویسندگان
چکیده
Development of a vaccine(s) based on sperm antigens represents a promising approach for contraception. The utility of an antigen in immunocontraception is contingent upon its testis/sperm specificity and involvement in spermatogenesis and/or fertilization. The aim of the present article is to review the information regarding the proteins that have been reported to be testis/sperm-specific and may have an important function in spermatogenesis and/or fertilization. The potential role of these proteins in the development an antisperm contraceptive vaccine(s) is discussed.
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ورودعنوان ژورنال:
- Frontiers in bioscience : a journal and virtual library
دوره 3 شماره
صفحات -
تاریخ انتشار 1998